The effect of left ventricular myocardial hypertrophy on noninvasive parameters of myocardial work in patients in the postinfarction period 

Olga D. Vershinina, Postgraduate student, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: poloz.ol@yandex.ru
Alena V. Golubeva, Candidate of medical sciences, senior lecturer of the sub-department of therapy, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: fialmy@mail.ru
Anastasia V. Shcherbinina, Candidate of medical sciences, senior lecturer of the sub-department of therapy, Medical Institute, Penza State University (40 Krasnaya street, Penza, Russia), E-mail: anastasya.babina@gmail.com

Background. The purpose of the study was to determine the values of noninvasive parameters of myocardial work in patients with acute myocardial infarction (MI) with and without ST segment elevation in various types of left ventricular (LV) myocardial hypertrophy. Materials and methods. The study included 120 people who met the inclusion criteria. Standard and speckle-tracking echocardiography (EchoCG) with automatic calculation of noninvasive parameters of myocardial work was performed in all patients on days 7- 9 and 24 weeks after MI. Results. All patients at 24 weeks of follow–up were divided into four groups depending on the type of LV hypertrophy according to EchoCG data: the group without hypertrophic changes (“without LVH”) – 22 (18.3 %) patients; the group with concentric LV remodeling (“CRofLV”) – 44 (36.7 %) people, the group with concentric LV hypertrophy (“CHofLV”) united 34 (28.3 %) patients; the group with eccentric LV hypertrophy (“EHofLV”) was diagnosed in 20 (16.7 %) individuals. Higher GWW values (p=0.003) and lower GWE values (p=0.003) were determined in the group with “CHofLV”. It was also revealed that in patients with EHofLV, both standard EchoCG parameters and non-invasive parameters of myocardial work were worse. Thus, LVEF in the CRofLV group was 18 % higher than in the EHofLV group, and GLS by 27 %. GWE and GCW had higher values in the CRofLV group. The GWW value in the EHofLV group was 2 times higher than the same parameter in the CRofLV group. Conclusions. Such parameters of noninvasive assessment of myocardial work as GWW, GWE, and to some extent GCW depend on the type of LV myocardial hypertrophy.

myocardial infarction, myocardial hypertrophy, echocardiography, speckle tracking echocardiography, noninvasive parameters of myocardial work

Vershinina O.D., Golubeva A.V., Shcherbinina A.V. The effect of left ventricular myocardial hypertrophy on noninvasive parameters of myocardial work in patients in the postinfarction period. Izvestiya vysshikh uchebnykh zavedeniy. Povolzhskiy region. Meditsinskie nauki = University proceedings. Volga region. Medical sciences. 2023;(4):75–86. (In Russ.). doi: 10.21685/2072-3032-2024-4-6